TRIM72 Alleviates Muscle Inflammation in mdx Mice via Promoting Mitophagy-Mediated NLRP3 Inflammasome Inactivation

Chronic muscle inflammation exacerbates the pathogenesis of Duchenne muscular dystrophy (DMD), which is characterized by progressive muscle degeneration and weakness. NLRP3 (nucleotide-binding domain and leucine-rich repeat pyrin domain containing 3) inflammasome plays a key role in the inflammatory...

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Detalles Bibliográficos
Autores principales: Wu, Mengli, Li, Huan, He, Juanjuan, Liang, Jiahui, Liu, Yanmei, Zhang, Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876702/
https://www.ncbi.nlm.nih.gov/pubmed/36713032
http://dx.doi.org/10.1155/2023/8408574

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