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Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis

We herein report a 20-year-old woman who developed eosinophilic granulomatosis with polyangiitis (EGPA) and portal vein thrombosis (PVT). EGPA was diagnosed based on the patient's history of asthma, hypereosinophilia, and mononeuritis complex. Thrombocytopenia and liver dysfunction were observe...

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Autores principales: Oka, Naoya, Yoshida, Yusuke, Sugimoto, Tomohiro, Yorishima, Ai, Masuda, Sho, Hirata, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876703/
https://www.ncbi.nlm.nih.gov/pubmed/35705273
http://dx.doi.org/10.2169/internalmedicine.9485-22
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author Oka, Naoya
Yoshida, Yusuke
Sugimoto, Tomohiro
Yorishima, Ai
Masuda, Sho
Hirata, Shintaro
author_facet Oka, Naoya
Yoshida, Yusuke
Sugimoto, Tomohiro
Yorishima, Ai
Masuda, Sho
Hirata, Shintaro
author_sort Oka, Naoya
collection PubMed
description We herein report a 20-year-old woman who developed eosinophilic granulomatosis with polyangiitis (EGPA) and portal vein thrombosis (PVT). EGPA was diagnosed based on the patient's history of asthma, hypereosinophilia, and mononeuritis complex. Thrombocytopenia and liver dysfunction were observed, necessitating contrast-enhanced computed tomography (CECT), which revealed PVT. Her symptoms soon improved with glucocorticoids and anticoagulation therapy. As patients with EGPA often suffer from asthma, they can be hesitant to undergo CECT. However, if patients with EGPA show uncertain thrombocytopenia with liver dysfunction, a further evaluation using CECT is warranted to detect PVT.
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spelling pubmed-98767032023-02-02 Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis Oka, Naoya Yoshida, Yusuke Sugimoto, Tomohiro Yorishima, Ai Masuda, Sho Hirata, Shintaro Intern Med Case Report We herein report a 20-year-old woman who developed eosinophilic granulomatosis with polyangiitis (EGPA) and portal vein thrombosis (PVT). EGPA was diagnosed based on the patient's history of asthma, hypereosinophilia, and mononeuritis complex. Thrombocytopenia and liver dysfunction were observed, necessitating contrast-enhanced computed tomography (CECT), which revealed PVT. Her symptoms soon improved with glucocorticoids and anticoagulation therapy. As patients with EGPA often suffer from asthma, they can be hesitant to undergo CECT. However, if patients with EGPA show uncertain thrombocytopenia with liver dysfunction, a further evaluation using CECT is warranted to detect PVT. The Japanese Society of Internal Medicine 2022-06-14 2023-01-01 /pmc/articles/PMC9876703/ /pubmed/35705273 http://dx.doi.org/10.2169/internalmedicine.9485-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Oka, Naoya
Yoshida, Yusuke
Sugimoto, Tomohiro
Yorishima, Ai
Masuda, Sho
Hirata, Shintaro
Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title_full Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title_fullStr Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title_full_unstemmed Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title_short Portal Vein Thrombosis as a Cause of Undetermined Thrombocytopenia with Liver Dysfunction in a Patient with Eosinophilic Granulomatosis with Polyangiitis
title_sort portal vein thrombosis as a cause of undetermined thrombocytopenia with liver dysfunction in a patient with eosinophilic granulomatosis with polyangiitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876703/
https://www.ncbi.nlm.nih.gov/pubmed/35705273
http://dx.doi.org/10.2169/internalmedicine.9485-22
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