Pulmonary Nodular Lymphoid Hyperplasia Evaluated with Bronchoalveolar Lavage Fluid Findings: A Case Report and Review of the Literature on Japanese Patients

Pulmonary nodular lymphoid hyperplasia (PNLH) is a very rare disease, and it is difficult to diagnose PNLH and distinguish it from mucosa-associated lymphoid tissue (MALT) lymphoma. In addition, information on bronchoalveolar lavage fluid (BALF) analyses is lacking. We herein report a 36-year-old Ja...

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Detalles Bibliográficos
Autores principales: Moriyama, Sakiko, Kido, Takashi, Sakamoto, Noriho, Fuchigami, Mai, Tokito, Takatomo, Okuno, Daisuke, Miyamura, Takuto, Nakashima, Shota, Hara, Atsuko, Ishimoto, Hiroshi, Imaizumi, Yoshitaka, Tsuruda, Kazuto, Yanagihara, Katsunori, Fukuoka, Junya, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876723/
https://www.ncbi.nlm.nih.gov/pubmed/36596475
http://dx.doi.org/10.2169/internalmedicine.9310-21
Descripción
Sumario:Pulmonary nodular lymphoid hyperplasia (PNLH) is a very rare disease, and it is difficult to diagnose PNLH and distinguish it from mucosa-associated lymphoid tissue (MALT) lymphoma. In addition, information on bronchoalveolar lavage fluid (BALF) analyses is lacking. We herein report a 36-year-old Japanese woman diagnosed with PLNH by a surgical biopsy and analysis of BALF. The BALF showed an increase in B-cell marker-positive lymphocytes, normal patterns of B-cell clonality, mucosa-associated lymphoid tissue 1 gene, and immunoglobulin heavy chain at 14q32 translocations. We also reviewed Japanese cases of PNLH described in Japanese or English to explore the characteristics of such cases.

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