Combined treatments with AZD5363, AZD8542, curcumin or resveratrol induce death of human glioblastoma cells by suppressing the PI3K/AKT and SHH signaling pathways

Glioblastoma (GBM) is a very aggressive tumor that presents vascularization, necrosis and is resistant to chemotherapy and radiotherapy. Current treatments are not effective eradicating GBM, thus, there is an urgent need to develop novel therapeutic strategies against GBM. AZD5363, AZD8542, curcumin...

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Detalles Bibliográficos
Autores principales: Mejía-Rodríguez, Rosalinda, Romero-Trejo, Daniel, González, Rosa O., Segovia, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876780/
https://www.ncbi.nlm.nih.gov/pubmed/36714540
http://dx.doi.org/10.1016/j.bbrep.2023.101430

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