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A wearable cardiac ultrasound imager

Continuous imaging of cardiac functions is highly desirable for the assessment of long-term cardiovascular health, detection of acute cardiac dysfunction and clinical management of critically ill or surgical patients(1–4). However, conventional non-invasive approaches to image the cardiac function c...

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Autores principales: Hu, Hongjie, Huang, Hao, Li, Mohan, Gao, Xiaoxiang, Yin, Lu, Qi, Ruixiang, Wu, Ray S., Chen, Xiangjun, Ma, Yuxiang, Shi, Keren, Li, Chenghai, Maus, Timothy M., Huang, Brady, Lu, Chengchangfeng, Lin, Muyang, Zhou, Sai, Lou, Zhiyuan, Gu, Yue, Chen, Yimu, Lei, Yusheng, Wang, Xinyu, Wang, Ruotao, Yue, Wentong, Yang, Xinyi, Bian, Yizhou, Mu, Jing, Park, Geonho, Xiang, Shu, Cai, Shengqiang, Corey, Paul W., Wang, Joseph, Xu, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876798/
https://www.ncbi.nlm.nih.gov/pubmed/36697864
http://dx.doi.org/10.1038/s41586-022-05498-z
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author Hu, Hongjie
Huang, Hao
Li, Mohan
Gao, Xiaoxiang
Yin, Lu
Qi, Ruixiang
Wu, Ray S.
Chen, Xiangjun
Ma, Yuxiang
Shi, Keren
Li, Chenghai
Maus, Timothy M.
Huang, Brady
Lu, Chengchangfeng
Lin, Muyang
Zhou, Sai
Lou, Zhiyuan
Gu, Yue
Chen, Yimu
Lei, Yusheng
Wang, Xinyu
Wang, Ruotao
Yue, Wentong
Yang, Xinyi
Bian, Yizhou
Mu, Jing
Park, Geonho
Xiang, Shu
Cai, Shengqiang
Corey, Paul W.
Wang, Joseph
Xu, Sheng
author_facet Hu, Hongjie
Huang, Hao
Li, Mohan
Gao, Xiaoxiang
Yin, Lu
Qi, Ruixiang
Wu, Ray S.
Chen, Xiangjun
Ma, Yuxiang
Shi, Keren
Li, Chenghai
Maus, Timothy M.
Huang, Brady
Lu, Chengchangfeng
Lin, Muyang
Zhou, Sai
Lou, Zhiyuan
Gu, Yue
Chen, Yimu
Lei, Yusheng
Wang, Xinyu
Wang, Ruotao
Yue, Wentong
Yang, Xinyi
Bian, Yizhou
Mu, Jing
Park, Geonho
Xiang, Shu
Cai, Shengqiang
Corey, Paul W.
Wang, Joseph
Xu, Sheng
author_sort Hu, Hongjie
collection PubMed
description Continuous imaging of cardiac functions is highly desirable for the assessment of long-term cardiovascular health, detection of acute cardiac dysfunction and clinical management of critically ill or surgical patients(1–4). However, conventional non-invasive approaches to image the cardiac function cannot provide continuous measurements owing to device bulkiness(5–11), and existing wearable cardiac devices can only capture signals on the skin(12–16). Here we report a wearable ultrasonic device for continuous, real-time and direct cardiac function assessment. We introduce innovations in device design and material fabrication that improve the mechanical coupling between the device and human skin, allowing the left ventricle to be examined from different views during motion. We also develop a deep learning model that automatically extracts the left ventricular volume from the continuous image recording, yielding waveforms of key cardiac performance indices such as stroke volume, cardiac output and ejection fraction. This technology enables dynamic wearable monitoring of cardiac performance with substantially improved accuracy in various environments.
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spelling pubmed-98767982023-01-27 A wearable cardiac ultrasound imager Hu, Hongjie Huang, Hao Li, Mohan Gao, Xiaoxiang Yin, Lu Qi, Ruixiang Wu, Ray S. Chen, Xiangjun Ma, Yuxiang Shi, Keren Li, Chenghai Maus, Timothy M. Huang, Brady Lu, Chengchangfeng Lin, Muyang Zhou, Sai Lou, Zhiyuan Gu, Yue Chen, Yimu Lei, Yusheng Wang, Xinyu Wang, Ruotao Yue, Wentong Yang, Xinyi Bian, Yizhou Mu, Jing Park, Geonho Xiang, Shu Cai, Shengqiang Corey, Paul W. Wang, Joseph Xu, Sheng Nature Article Continuous imaging of cardiac functions is highly desirable for the assessment of long-term cardiovascular health, detection of acute cardiac dysfunction and clinical management of critically ill or surgical patients(1–4). However, conventional non-invasive approaches to image the cardiac function cannot provide continuous measurements owing to device bulkiness(5–11), and existing wearable cardiac devices can only capture signals on the skin(12–16). Here we report a wearable ultrasonic device for continuous, real-time and direct cardiac function assessment. We introduce innovations in device design and material fabrication that improve the mechanical coupling between the device and human skin, allowing the left ventricle to be examined from different views during motion. We also develop a deep learning model that automatically extracts the left ventricular volume from the continuous image recording, yielding waveforms of key cardiac performance indices such as stroke volume, cardiac output and ejection fraction. This technology enables dynamic wearable monitoring of cardiac performance with substantially improved accuracy in various environments. Nature Publishing Group UK 2023-01-25 2023 /pmc/articles/PMC9876798/ /pubmed/36697864 http://dx.doi.org/10.1038/s41586-022-05498-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hu, Hongjie
Huang, Hao
Li, Mohan
Gao, Xiaoxiang
Yin, Lu
Qi, Ruixiang
Wu, Ray S.
Chen, Xiangjun
Ma, Yuxiang
Shi, Keren
Li, Chenghai
Maus, Timothy M.
Huang, Brady
Lu, Chengchangfeng
Lin, Muyang
Zhou, Sai
Lou, Zhiyuan
Gu, Yue
Chen, Yimu
Lei, Yusheng
Wang, Xinyu
Wang, Ruotao
Yue, Wentong
Yang, Xinyi
Bian, Yizhou
Mu, Jing
Park, Geonho
Xiang, Shu
Cai, Shengqiang
Corey, Paul W.
Wang, Joseph
Xu, Sheng
A wearable cardiac ultrasound imager
title A wearable cardiac ultrasound imager
title_full A wearable cardiac ultrasound imager
title_fullStr A wearable cardiac ultrasound imager
title_full_unstemmed A wearable cardiac ultrasound imager
title_short A wearable cardiac ultrasound imager
title_sort wearable cardiac ultrasound imager
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876798/
https://www.ncbi.nlm.nih.gov/pubmed/36697864
http://dx.doi.org/10.1038/s41586-022-05498-z
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