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X-chromosome inactivation patterns depend on age and tissue but not conception method in humans

Female somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes, randomly silencing the maternal or paternal X chromosome in each cell of 46,XX females. Skewed XCI toward one parental X has been observed in association with ageing and in some female car...

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Detalles Bibliográficos
Autores principales:	Juchniewicz, Patrycja, Kloska, Anna, Portalska, Karolina, Jakóbkiewicz-Banecka, Joanna, Węgrzyn, Grzegorz, Liss, Joanna, Głodek, Piotr, Tukaj, Stefan, Piotrowska, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877087/ https://www.ncbi.nlm.nih.gov/pubmed/36695960 http://dx.doi.org/10.1007/s10577-023-09717-9

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