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Cryo‐EM structure of orphan G protein‐coupled receptor GPR21

GPR21 belongs to class A orphan G protein‐coupled receptor (GPCR). The endogenous ligands for human GPR21 remain unidentified. GPR21 expression is associated with developing type 2 diabetes (T2DM), a multifactorial metabolic disease caused by pancreatic β‐cell dysfunction, decreasing insulin product...

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Detalles Bibliográficos
Autores principales:	Wong, Thian‐Sze, Gao, Wei, Chen, Geng, Qiu, Chen, He, Guodong, Ye, Fang, Wu, Zhangsong, Zeng, Zicheng, Du, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877262/ https://www.ncbi.nlm.nih.gov/pubmed/36721851 http://dx.doi.org/10.1002/mco2.205

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