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mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine

BACKGROUND: The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS-CoV-2 and code for its spike (S) protein. Several studies have investigated short-term antibody (Ab) responses after vaccination. OBJEC...

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Detalles Bibliográficos
Autores principales: Buhre, Jana Sophia, Pongracz, Tamas, Künsting, Inga, Lixenfeld, Anne S., Wang, Wenjun, Nouta, Jan, Lehrian, Selina, Schmelter, Franziska, Lunding, Hanna B., Dühring, Lara, Kern, Carsten, Petry, Janina, Martin, Emily L., Föh, Bandik, Steinhaus, Moritz, von Kopylow, Vera, Sina, Christian, Graf, Tobias, Rahmöller, Johann, Wuhrer, Manfred, Ehlers, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877300/
https://www.ncbi.nlm.nih.gov/pubmed/36713457
http://dx.doi.org/10.3389/fimmu.2022.1020844