Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL receptor and apolipoprotein E, are widely use...

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Detalles Bibliográficos
Autores principales: Fuller, Mark T., Dadoo, Omid, Xiong, Ting, Chivukula, Pardh, MacDonald, Melissa E., Lee, Samuel K., Austin, Richard C., Igdoura, Suleiman A., Trigatti, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877335/
https://www.ncbi.nlm.nih.gov/pubmed/36714321
http://dx.doi.org/10.3389/fphys.2022.1023397

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