Cargando…

Role of Connexin 43 phosphorylation on Serine-368 by PKC in cardiac function and disease

Intercellular communication mediated by gap junction channels and hemichannels composed of Connexin 43 (Cx43) is vital for the propagation of electrical impulses through cardiomyocytes. The carboxyl terminal tail of Cx43 undergoes various post-translational modifications including phosphorylation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pun, Renju, Kim, Michael H., North, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877470/ https://www.ncbi.nlm.nih.gov/pubmed/36712244 http://dx.doi.org/10.3389/fcvm.2022.1080131

Ejemplares similares

Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication
por: Lampe, Paul D., et al.
Publicado: (2000)

Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368
por: Li, Wei Chao, et al.
Publicado: (2019)

The Role of Phosphorylated Cx43 on PKC Mediated Ser368 in Lung Injury Induced by Seawater Inhalation
por: Liu, Tonggang, et al.
Publicado: (2015)

Trastuzumab and Doxorubicin Sequential Administration Increases Oxidative Stress and Phosphorylation of Connexin 43 on Ser368
por: Pecoraro, Michela, et al.
Publicado: (2022)

Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368
por: Richards, Theresa S., et al.
Publicado: (2004)

Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy
por: Wei, Xing, et al.
Publicado: (2022)

Expression of connexin 43 protein in cardiomyocytes of heart failure mouse model
por: Liu, Shaoyan, et al.
Publicado: (2022)

Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization
por: Nimlamool, Wutigri, et al.
Publicado: (2015)

Involvement of PKCε in FSH-induced connexin43 phosphorylation and oocyte maturation in mouse
por: Cai, Han, et al.
Publicado: (2018)

Up‐regulated Cx43 phosphorylation at Ser368 prolongs QRS duration in myocarditis
por: Zhong, Chunlian, et al.
Publicado: (2018)

Connexin 43 Phosphorylation: Implications in Multiple Diseases
por: Zhang, Meng, et al.
Publicado: (2023)

Role and Mechanism of PKC-δ for Cardiovascular Disease: Current Status and Perspective
por: Miao, Li-na, et al.
Publicado: (2022)

ODP368 Hyper-phosphorylation of β-catenin at Serine552: predictive marker of invasion and recurrence of Non-Functioning Pituitary Tumours (NFPTs)
por: Rai, Ashutosh, et al.
Publicado: (2022)

Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013)

Function of Connexin-43 in Macrophages
por: Rodjakovic, Daniel, et al.
Publicado: (2021)

Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer
por: Naser Al Deen, Nataly, et al.
Publicado: (2019)

Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
por: Freitas-Andrade, Moises, et al.
Publicado: (2019)

LRP6-mediated phosphorylation of connexin43 in myocardial infarction
por: Zhang, Xu-min, et al.
Publicado: (2023)

The Role of Connexin 43 in Lung Disease
por: Swartzendruber, Julie A., et al.
Publicado: (2020)

Glycated serum albumin decreases connexin 43 phosphorylation in the corpus cavernosum
por: Huang, Yanping, et al.
Publicado: (2022)

Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine
por: Marsh, Spencer R., et al.
Publicado: (2021)

Spatial Heterogeneity of Cx43 is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats
por: Boulaksil, Mohamed, et al.
Publicado: (2016)

Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling
por: Rong, Bing, et al.
Publicado: (2016)

Remote ischemic preconditioning preserves Connexin 43 phosphorylation in the rat heart in vivo
por: Brandenburger, Timo, et al.
Publicado: (2014)

Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning
por: Hirschhäuser, Christine, et al.
Publicado: (2021)

Connexin 43 dephosphorylation at serine 282 induces spontaneous arrhythmia and increases susceptibility to ischemia/reperfusion injury
por: Wu, Lulin, et al.
Publicado: (2023)

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma
por: Luu, Savannah, et al.
Publicado: (2019)

Anti-arrhythmic Cardiac Phenotype Elicited by Chronic Intermittent Hypoxia Is Associated With Alterations in Connexin-43 Expression, Phosphorylation, and Distribution
por: Kohutova, Jana, et al.
Publicado: (2019)

Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms
por: Yaron, Jordan R., et al.
Publicado: (2021)

Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
Publicado: (1991)

Multifaceted Roles of Connexin 43 in Stem Cell Niches
por: Genet, Nafiisha, et al.
Publicado: (2018)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
por: Rusiecka, Olga M., et al.
Publicado: (2020)

Role of Connexin 43 in an Inflammatory Model for TMJ Hyperalgesia
por: Ahmed, Fabeeha, et al.
Publicado: (2021)

Run 368 P
por: Colchester, R J
Publicado: (1973)

S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function
por: Soetkamp, Daniel, et al.
Publicado: (2014)

Antidepressants Impact Connexin 43 Channel Functions in Astrocytes
por: Jeanson, Tiffany, et al.
Publicado: (2016)

Protein–Protein Interactions with Connexin 43: Regulation and Function
por: Sorgen, Paul L., et al.
Publicado: (2018)

Zonula occludens-1 and connexin 43 expression in the failing human heart
por: Kostin, Sawa
Publicado: (2007)

Short-term pacing in the mouse alters cardiac expression of connexin43
por: Kontogeorgis, Andrianos, et al.
Publicado: (2008)

Effect of Beta-Carotene on Oxidative Stress and Expression of Cardiac Connexin 43
por: Novo, Rosangela, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_34m8o8hsfipngloe4m5o7npqmg