Cargando…
Recent applications of computational methods to allosteric drug discovery
Interest in exploiting allosteric sites for the development of new therapeutics has grown considerably over the last two decades. The chief driving force behind the interest in allostery for drug discovery stems from the fact that in comparison to orthosteric sites, allosteric sites are less conserv...
Autores principales: | Govindaraj, Rajiv Gandhi, Thangapandian, Sundar, Schauperl, Michael, Denny, Rajiah Aldrin, Diller, David J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877542/ https://www.ncbi.nlm.nih.gov/pubmed/36710877 http://dx.doi.org/10.3389/fmolb.2022.1070328 |
Ejemplares similares
-
Recent Developments in Free Energy Calculations for Drug Discovery
por: King, Edward, et al.
Publicado: (2021) -
Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2
por: Sgrignani, Jacopo, et al.
Publicado: (2021) -
Application of Fragment-Based Drug Discovery to Versatile Targets
por: Li, Qingxin
Publicado: (2020) -
Application of Computational Methods in Understanding Mutations in Mycobacterium tuberculosis Drug Resistance
por: Mugumbate, Grace, et al.
Publicado: (2021) -
Recent Developments and Applications of the MMPBSA Method
por: Wang, Changhao, et al.
Publicado: (2018)