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Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation

AIM: The major clinical manifestations multisystem inflammatory syndrome in children (MIS‐C) are fever, gastrointestinal and cardiac. The aim of this study was to describe MIS‐C in a series of patients who presented primarily with cervical manifestations. METHODS: We retrospectively reviewed medical...

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Autores principales: Brooks, Rebecca, Fisher, Ron, Glicksman, Charlotte, Pollak, Uri, Simanovsky, Natalia, Berkun, Yackov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877739/
https://www.ncbi.nlm.nih.gov/pubmed/36495064
http://dx.doi.org/10.1111/apa.16623
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author Brooks, Rebecca
Fisher, Ron
Glicksman, Charlotte
Pollak, Uri
Simanovsky, Natalia
Berkun, Yackov
author_facet Brooks, Rebecca
Fisher, Ron
Glicksman, Charlotte
Pollak, Uri
Simanovsky, Natalia
Berkun, Yackov
author_sort Brooks, Rebecca
collection PubMed
description AIM: The major clinical manifestations multisystem inflammatory syndrome in children (MIS‐C) are fever, gastrointestinal and cardiac. The aim of this study was to describe MIS‐C in a series of patients who presented primarily with cervical manifestations. METHODS: We retrospectively reviewed medical records of all patients who met the Centers for Disease Control and Prevention and World Health Organization MIS‐C diagnostic criteria treated at Hadassah‐Hebrew University Medical Center between April 2020 and September 2021. RESULTS: Of 37 children diagnosed with MIS‐C (median age: 10.2 years, range 1.5–18 years, 20 male) five, 13.5% (median age: 14.4 years, range 9.2–17.5 years) presented with cervical symptoms mimicking neck infections. One was hospitalised with a working diagnosis of retropharyngeal abscess, and four with acute cervical lymphadenitis that did not respond to early antibiotic treatment. All developed full MIS‐C phenotype. CONCLUSION: MIS‐C may present as cervical inflammation. An ill‐appearing child with symptoms and/or signs of cervical inflammation should be evaluated for clinical and laboratory features of MIS‐C, thereby facilitating prompt treatment of this potentially fatal disorder.
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spelling pubmed-98777392023-01-26 Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation Brooks, Rebecca Fisher, Ron Glicksman, Charlotte Pollak, Uri Simanovsky, Natalia Berkun, Yackov Acta Paediatr Original Articles AIM: The major clinical manifestations multisystem inflammatory syndrome in children (MIS‐C) are fever, gastrointestinal and cardiac. The aim of this study was to describe MIS‐C in a series of patients who presented primarily with cervical manifestations. METHODS: We retrospectively reviewed medical records of all patients who met the Centers for Disease Control and Prevention and World Health Organization MIS‐C diagnostic criteria treated at Hadassah‐Hebrew University Medical Center between April 2020 and September 2021. RESULTS: Of 37 children diagnosed with MIS‐C (median age: 10.2 years, range 1.5–18 years, 20 male) five, 13.5% (median age: 14.4 years, range 9.2–17.5 years) presented with cervical symptoms mimicking neck infections. One was hospitalised with a working diagnosis of retropharyngeal abscess, and four with acute cervical lymphadenitis that did not respond to early antibiotic treatment. All developed full MIS‐C phenotype. CONCLUSION: MIS‐C may present as cervical inflammation. An ill‐appearing child with symptoms and/or signs of cervical inflammation should be evaluated for clinical and laboratory features of MIS‐C, thereby facilitating prompt treatment of this potentially fatal disorder. John Wiley and Sons Inc. 2022-12-20 /pmc/articles/PMC9877739/ /pubmed/36495064 http://dx.doi.org/10.1111/apa.16623 Text en © 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Brooks, Rebecca
Fisher, Ron
Glicksman, Charlotte
Pollak, Uri
Simanovsky, Natalia
Berkun, Yackov
Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title_full Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title_fullStr Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title_full_unstemmed Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title_short Multisystem inflammatory syndrome in children associated with COVID‐19 presenting as cervical inflammation
title_sort multisystem inflammatory syndrome in children associated with covid‐19 presenting as cervical inflammation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877739/
https://www.ncbi.nlm.nih.gov/pubmed/36495064
http://dx.doi.org/10.1111/apa.16623
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