Cargando…

Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19

Post‐acute sequelae of COVID‐19 (PASC) are long‐term consequences of SARS‐CoV‐2 infection that can substantially impair the quality of life. Underlying mechanisms ranging from persistent viruses to innate and adaptive immune dysregulation have been discussed. Here, we profiled the plasma of 181 indi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schultheiß, Christoph, Willscher, Edith, Paschold, Lisa, Gottschick, Cornelia, Klee, Bianca, Bosurgi, Lidia, Dutzmann, Jochen, Sedding, Daniel, Frese, Thomas, Girndt, Matthias, Höll, Jessica I., Gekle, Michael, Mikolajczyk, Rafael, Binder, Mascha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878213/ https://www.ncbi.nlm.nih.gov/pubmed/36458566 http://dx.doi.org/10.1002/jmv.28364

Ejemplares similares

The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
por: Schultheiß, Christoph, et al.
Publicado: (2022)

Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination
por: Paschold, Lisa, et al.
Publicado: (2022)

Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany: Results from the DigiHero Cohort
por: Klee, Bianca, et al.
Publicado: (2023)

Mental health in Germany in the first weeks of the Russo-Ukrainian war
por: Gottschick, Cornelia, et al.
Publicado: (2023)

Anxiety, depressive symptoms, and distress over the course of the war in Ukraine in three federal states in Germany
por: Massag, Janka, et al.
Publicado: (2023)

Immune signatures in variant syndromes of primary biliary cholangitis and autoimmune hepatitis
por: Schultheiß, Christoph, et al.
Publicado: (2023)

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
por: Schultheiß, Christoph, et al.
Publicado: (2021)

Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
por: Schultheiß, Christoph, et al.
Publicado: (2020)

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation
por: Cheng, Mary Hongying, et al.
Publicado: (2020)

T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort
por: Paschold, Lisa, et al.
Publicado: (2023)

Birth cohort studies using symptom diaries for assessing respiratory diseases–a scoping review
por: Langer, Susan, et al.
Publicado: (2022)

Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts
por: Simnica, Donjete, et al.
Publicado: (2021)

Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients
por: Grimm, Juliane, et al.
Publicado: (2022)

The risk of indoor sports and culture events for the transmission of COVID-19
por: Moritz, Stefan, et al.
Publicado: (2021)

Circulating Tumor DNA in Gastric and Gastroesophageal Junction Cancer
por: Paschold, Lisa, et al.
Publicado: (2022)

Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21(R110) chronic lymphocytic leukemia
por: Paschold, Lisa, et al.
Publicado: (2022)

First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
por: Paschold, Lisa, et al.
Publicado: (2023)

PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition
por: Claaß, Luise Victoria, et al.
Publicado: (2022)

Overcoming unintended immunogenicity in immunocompetent mouse models of metastasis: the case of GFP
por: Schultheiß, Christoph, et al.
Publicado: (2022)

Knowledge, Vaccination Status, and Reasons for Avoiding Vaccinations against Hepatitis B in Developing Countries: A Systematic Review
por: Machmud, Putri Bungsu, et al.
Publicado: (2021)

Barriers to and Facilitators of Hepatitis B Vaccination among the Adult Population in Indonesia: A Mixed Methods Study
por: Machmud, Putri Bungsu, et al.
Publicado: (2023)

Development of the simulation-based German albuminuria screening model (S-GASM) for estimating the cost-effectiveness of albuminuria screening in Germany
por: Kairys, Paul, et al.
Publicado: (2022)

SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
por: von Wenserski, Lisa, et al.
Publicado: (2020)

Evolutionary clonal trajectories in nodular lymphocyte-predominant Hodgkin lymphoma with high risk of transformation
por: Paschold, Lisa, et al.
Publicado: (2021)

B cells in autoimmune hepatitis: bystanders or central players?
por: Schultheiß, Christoph, et al.
Publicado: (2022)

Reduced proliferation of bone marrow MSC after allogeneic stem cell transplantation is associated with clinical outcome
por: Katzerke, Christiane, et al.
Publicado: (2023)

Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma
por: Brandt, Anna, et al.
Publicado: (2023)

Emerging translational approaches to target STAT3 signalling and its impact on vascular disease
por: Dutzmann, Jochen, et al.
Publicado: (2015)

Pseudotime Dynamics in Melanoma Single-Cell Transcriptomes Reveals Different Mechanisms of Tumor Progression
por: Loeffler-Wirth, Henry, et al.
Publicado: (2018)

Impact of bone marrow involvement on outcome in relapsed and refractory transplant eligible diffuse large B-cell lymphoma and transformed indolent lymphoma
por: Terziev, Denis, et al.
Publicado: (2020)

Disease and Treatment-Related Sequelae in Patients with Complex Jugulotympanic Paraganglioma
por: Harati, Ali, et al.
Publicado: (2018)

PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
por: Stein, Alexander, et al.
Publicado: (2021)

Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
por: Tintelnot, Joseph, et al.
Publicado: (2022)

Safety and efficacy of renal sympathetic denervation: a 9-year long-term follow-up of 24-hour ambulatory blood pressure measurements
por: Vogt, Alexander, et al.
Publicado: (2023)

Detection of SARS-CoV-2 Derived Small RNAs and Changes in Circulating Small RNAs Associated with COVID-19
por: Grehl, Claudius, et al.
Publicado: (2021)

Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
por: Porritt, Rebecca A, et al.
Publicado: (2020)

Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort
por: Löffler-Wirth, Henry, et al.
Publicado: (2016)

Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation
por: Daniel, Jan-Marcus, et al.
Publicado: (2012)

Effect of intermittent fasting after ST-elevation myocardial infarction on left ventricular function: study protocol of a pilot randomised controlled trial (INTERFAST-MI)
por: Dutzmann, Jochen, et al.
Publicado: (2022)

Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease
por: Sedding, Daniel G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i9ijkp55trqcqmvmtk490ohb2u