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Strategies to Prevent Transmission of Candida auris in Healthcare Settings
PURPOSE OF REVIEW: Candida auris, a recently recognized yeast pathogen, has become a major public health threat due to the problems associated with its accurate identification, intrinsic and acquired resistance to antifungal drugs, and its potential to easily contaminate the environment causing clon...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878498/ https://www.ncbi.nlm.nih.gov/pubmed/36718372 http://dx.doi.org/10.1007/s12281-023-00451-7 |
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author | Ahmad, Suhail Asadzadeh, Mohammad |
author_facet | Ahmad, Suhail Asadzadeh, Mohammad |
author_sort | Ahmad, Suhail |
collection | PubMed |
description | PURPOSE OF REVIEW: Candida auris, a recently recognized yeast pathogen, has become a major public health threat due to the problems associated with its accurate identification, intrinsic and acquired resistance to antifungal drugs, and its potential to easily contaminate the environment causing clonal outbreaks in healthcare facilities. These outbreaks are associated with high mortality rates particularly among older patients with multiple comorbidities under intensive care settings. The purpose of this review is to highlight strategies that are being adapted to prevent transmission of C. auris in healthcare settings. RECENT FINDINGS: Colonized patients shed C. auris into their environment which contaminates surrounding equipment. It resists elimination even by robust decontamination procedures and is easily transmitted to new patients during close contact resulting in outbreaks. Efforts are being made to rapidly identify C. auris-infected/C. auris-colonized patients, to determine its susceptibility to antifungals, and to perform effective cleaning and decontamination of the environment and isolation of colonized patients to prevent further transmission. SUMMARY: Rapid and accurate identification of hospitalized patients infected/colonized with C. auris, rapid detection of its susceptibility patterns, and appropriate use of infection control measures can help to contain the spread of this highly pathogenic yeast in healthcare settings and prevent/control outbreaks. |
format | Online Article Text |
id | pubmed-9878498 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-98784982023-01-26 Strategies to Prevent Transmission of Candida auris in Healthcare Settings Ahmad, Suhail Asadzadeh, Mohammad Curr Fungal Infect Rep Article PURPOSE OF REVIEW: Candida auris, a recently recognized yeast pathogen, has become a major public health threat due to the problems associated with its accurate identification, intrinsic and acquired resistance to antifungal drugs, and its potential to easily contaminate the environment causing clonal outbreaks in healthcare facilities. These outbreaks are associated with high mortality rates particularly among older patients with multiple comorbidities under intensive care settings. The purpose of this review is to highlight strategies that are being adapted to prevent transmission of C. auris in healthcare settings. RECENT FINDINGS: Colonized patients shed C. auris into their environment which contaminates surrounding equipment. It resists elimination even by robust decontamination procedures and is easily transmitted to new patients during close contact resulting in outbreaks. Efforts are being made to rapidly identify C. auris-infected/C. auris-colonized patients, to determine its susceptibility to antifungals, and to perform effective cleaning and decontamination of the environment and isolation of colonized patients to prevent further transmission. SUMMARY: Rapid and accurate identification of hospitalized patients infected/colonized with C. auris, rapid detection of its susceptibility patterns, and appropriate use of infection control measures can help to contain the spread of this highly pathogenic yeast in healthcare settings and prevent/control outbreaks. Springer US 2023-01-26 2023 /pmc/articles/PMC9878498/ /pubmed/36718372 http://dx.doi.org/10.1007/s12281-023-00451-7 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Ahmad, Suhail Asadzadeh, Mohammad Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title | Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title_full | Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title_fullStr | Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title_full_unstemmed | Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title_short | Strategies to Prevent Transmission of Candida auris in Healthcare Settings |
title_sort | strategies to prevent transmission of candida auris in healthcare settings |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878498/ https://www.ncbi.nlm.nih.gov/pubmed/36718372 http://dx.doi.org/10.1007/s12281-023-00451-7 |
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