Cargando…
H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/β-catenin and TGF-β pathways
BACKGROUND: Uterine leiomyomas (UL) are the most common benign tumor in women of reproductive age. Their pathology remains unclear, which hampers the development of safe and effective treatments. Raising evidence suggests epigenetics as a main mechanism involved in tumor development. Histone modific...
Autores principales: | Carbajo-García, María Cristina, Juarez-Barber, Elena, Segura-Benítez, Marina, Faus, Amparo, Trelis, Alexandra, Monleón, Javier, Carmona-Antoñanzas, Greta, Pellicer, Antonio, Flanagan, James M., Ferrero, Hortensia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878797/ https://www.ncbi.nlm.nih.gov/pubmed/36703136 http://dx.doi.org/10.1186/s12958-023-01060-2 |
Ejemplares similares
-
5-aza-2′-deoxycitidine inhibits cell proliferation, extracellular matrix formation and Wnt/β-catenin pathway in human uterine leiomyomas
por: Carbajo-García, María Cristina, et al.
Publicado: (2021) -
Deciphering the Role of Histone Modifications in Uterine Leiomyoma: Acetylation of H3K27 Regulates the Expression of Genes Involved in Proliferation, Cell Signaling, Cell Transport, Angiogenesis and Extracellular Matrix Formation
por: Carbajo-García, María Cristina, et al.
Publicado: (2022) -
Proteomic analysis of extracellular vesicles secreted by primary human epithelial endometrial cells reveals key proteins related to embryo implantation
por: Segura-Benítez, Marina, et al.
Publicado: (2022) -
Establishment of Adenomyosis Organoids as a Preclinical Model to Study Infertility
por: Juárez-Barber, Elena, et al.
Publicado: (2022) -
Improved Models of Human Endometrial Organoids Based on Hydrogels from Decellularized Endometrium
por: Francés-Herrero, Emilio, et al.
Publicado: (2021)