Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline metabolism

ABSTRACT: Liver fibrosis is a chronic liver disease with the presence of progressive wound healing response caused by liver injury. Currently, there are no approved therapies for liver fibrosis. Exosomes derived from human adipose mesenchymal stem cells (hADMSCs-Exo) have displayed a prominent thera...

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Detalles Bibliográficos
Autores principales: Zhang, Zilong, Shang, Jin, Yang, Qinyan, Dai, Zonglin, Liang, Yuxin, Lai, Chunyou, Feng, Tianhang, Zhong, Deyuan, Zou, Haibo, Sun, Lelin, Su, Yuhao, Yan, Su, Chen, Jie, Yao, Yutong, Shi, Ying, Huang, Xiaolun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878808/
https://www.ncbi.nlm.nih.gov/pubmed/36698192
http://dx.doi.org/10.1186/s12951-023-01788-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878808/
https://www.ncbi.nlm.nih.gov/pubmed/36698192
http://dx.doi.org/10.1186/s12951-023-01788-4

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