Relative adrenal insufficiency is a risk factor and endotype of sepsis - A proof-of-concept study to support a precision medicine approach to guide glucocorticoid therapy for sepsis

INTRODUCTION: 25-60% of septic patients experience relative adrenal insufficiency (RAI) and glucocorticoid (GC) is frequently used in septic patients. However, the efficacy of GC therapy and whether GC therapy should be based on the status of RAI are highly controversial. Our poor understanding abou...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Hua, Guo, Ling, Hao, Dan, Wang, Qian, Ye, Xiang, Ito, Misa, Huang, Bin, Mineo, Chieko, Shaul, Philip W., Li, Xiang-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878847/
https://www.ncbi.nlm.nih.gov/pubmed/36713379
http://dx.doi.org/10.3389/fimmu.2022.1110516

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