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Characteristics associated with quality of life in the early stages of Mycosis Fungoides

BACKGROUND: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI)....

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Autores principales: Nourmohammadpour, Pedram, Nasimi, Maryam, Aryanian, Zeinab, Goodarzi, Azadeh, Jahazi, Reyhaneh, Etesami, Ifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878892/
https://www.ncbi.nlm.nih.gov/pubmed/36741488
http://dx.doi.org/10.22088/cjim.14.1.16
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author Nourmohammadpour, Pedram
Nasimi, Maryam
Aryanian, Zeinab
Goodarzi, Azadeh
Jahazi, Reyhaneh
Etesami, Ifa
author_facet Nourmohammadpour, Pedram
Nasimi, Maryam
Aryanian, Zeinab
Goodarzi, Azadeh
Jahazi, Reyhaneh
Etesami, Ifa
author_sort Nourmohammadpour, Pedram
collection PubMed
description BACKGROUND: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI). METHODS: Thirty MF patients (21 females/9 males) with a mean age of 46.73±15.9 years and in the early stages of the disease (26 stage Ι and 4 stage ΙΙ) were enrolled and were asked to fill the DLQI questionnaire. RESULTS: The mean DLQI score was 9.93±5.89. The QoL was largely affected by the disease in near half of the patients (46.7% of patients had a DLQI score11-20). QoL was significantly correlated with educational level and was more impaired in patients with lower educational status (DLQI score spearman rho=-0.382, P=0.037). QoL was not associated with sex, age, disease stage and disease duration. The symptom and feeling dimension of DLQI was significantly more impaired in patients with both patch and plaque compared to patch only (spearman rho= 0.397, P= 0.03). CONCLUSION: This study demonstrates how largely patients’ QoL is influenced in the early stages of MF, especially in patients with lower educational levels.
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spelling pubmed-98788922023-02-03 Characteristics associated with quality of life in the early stages of Mycosis Fungoides Nourmohammadpour, Pedram Nasimi, Maryam Aryanian, Zeinab Goodarzi, Azadeh Jahazi, Reyhaneh Etesami, Ifa Caspian J Intern Med Original Article BACKGROUND: Mycosis fungoides (MF) is a lymphoproliferative disorder characterized by skin-homing atypical lymphocytes. This study aimed to evaluate the quality of life (QoL) in MF patients in the early stages of the disease and the associated factors using the Dermatology Life Quality Index (DLQI). METHODS: Thirty MF patients (21 females/9 males) with a mean age of 46.73±15.9 years and in the early stages of the disease (26 stage Ι and 4 stage ΙΙ) were enrolled and were asked to fill the DLQI questionnaire. RESULTS: The mean DLQI score was 9.93±5.89. The QoL was largely affected by the disease in near half of the patients (46.7% of patients had a DLQI score11-20). QoL was significantly correlated with educational level and was more impaired in patients with lower educational status (DLQI score spearman rho=-0.382, P=0.037). QoL was not associated with sex, age, disease stage and disease duration. The symptom and feeling dimension of DLQI was significantly more impaired in patients with both patch and plaque compared to patch only (spearman rho= 0.397, P= 0.03). CONCLUSION: This study demonstrates how largely patients’ QoL is influenced in the early stages of MF, especially in patients with lower educational levels. Babol University of Medical Sciences 2023 /pmc/articles/PMC9878892/ /pubmed/36741488 http://dx.doi.org/10.22088/cjim.14.1.16 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nourmohammadpour, Pedram
Nasimi, Maryam
Aryanian, Zeinab
Goodarzi, Azadeh
Jahazi, Reyhaneh
Etesami, Ifa
Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title_full Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title_fullStr Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title_full_unstemmed Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title_short Characteristics associated with quality of life in the early stages of Mycosis Fungoides
title_sort characteristics associated with quality of life in the early stages of mycosis fungoides
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878892/
https://www.ncbi.nlm.nih.gov/pubmed/36741488
http://dx.doi.org/10.22088/cjim.14.1.16
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