Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and β-amyloid aggregation

Alzheimer disease (AD) is one of the major neurodegenerative diseases that could not be prevented or completely cured and may lead to death. Here, we target AChE and β-amyloid proteins. Synthesising new triphenylphosphporanylidene derivatives based on the surveyed literature and testing their biolog...

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Detalles Bibliográficos
Autores principales: El-Hussieny, Marwa, Abd-El-Maksoud, Mansoura A., Soliman, Fouad M., Fouad, Marwa A., El-Ashrey, Mohamed K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879200/
https://www.ncbi.nlm.nih.gov/pubmed/36695002
http://dx.doi.org/10.1080/14756366.2023.2166040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879200/
https://www.ncbi.nlm.nih.gov/pubmed/36695002
http://dx.doi.org/10.1080/14756366.2023.2166040

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