EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release

EKLF/Klf1 is a zinc-finger transcription activator essential for erythroid lineage commitment and terminal differentiation. Using ChIP-seq, we investigate EKLF DNA binding and transcription activation mechanisms during mouse embryonic erythropoiesis. We utilize the Nan/+ mouse that expresses the EKL...

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Detalles Bibliográficos
Autores principales: Mukherjee, Kaustav, Bieker, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879271/
https://www.ncbi.nlm.nih.gov/pubmed/36543143
http://dx.doi.org/10.1016/j.celrep.2022.111830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879271/
https://www.ncbi.nlm.nih.gov/pubmed/36543143
http://dx.doi.org/10.1016/j.celrep.2022.111830

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