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Endotyping COPD: hypoxia-inducible factor-2 as a molecular “switch” between the vascular and airway phenotypes?

COPD is a heterogeneous disease with multiple clinical phenotypes. COPD endotypes can be determined by different expressions of hypoxia-inducible factors (HIFs), which, in combination with individual susceptibility and environmental factors, may cause predominant airway or vascular changes in the lu...

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Detalles Bibliográficos
Autores principales: Myronenko, Oleh, Foris, Vasile, Crnkovic, Slaven, Olschewski, Andrea, Rocha, Sonia, Nicolls, Mark R., Olschewski, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879331/
https://www.ncbi.nlm.nih.gov/pubmed/36631133
http://dx.doi.org/10.1183/16000617.0173-2022