Cargando…
Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant
Type 1 diabetes patients carrying a ‘protective’ insulin gene (INS) variant present a disease endotype with reduced insulin antibody titers, preserved beta cell function and improved glycemic control. We tested whether this protective INS variant associated with lowered risk for development of proli...
Autores principales: | van Tienhoven, René, Vu, Anh Nguyet, Kaddis, John S., Roep, Bart O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879388/ https://www.ncbi.nlm.nih.gov/pubmed/36701305 http://dx.doi.org/10.1371/journal.pone.0280872 |
Ejemplares similares
-
Improving the Prediction of Type 1 Diabetes Across Ancestries
por: Kaddis, John S., et al.
Publicado: (2022) -
Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)
por: Roep, Bart O., et al.
Publicado: (2020) -
Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes
por: Gootjes, Chelsea, et al.
Publicado: (2022) -
Islet-Resident Dendritic Cells and Macrophages in Type 1 Diabetes: In Search of Bigfoot’s Print
por: Zirpel, Henner, et al.
Publicado: (2021) -
Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients
por: Nikolic, Tatjana, et al.
Publicado: (2022)