The small heat shock protein αB-Crystallin protects versus withaferin A-induced apoptosis and confers a more metastatic phenotype in cisplatin-resistant ovarian cancer cells

Since a majority of ovarian tumors recur in a drug-resistant form leaving patients few treatment options, the goal of this study was to explore phenotypic and molecular characteristics of a cisplatin-resistant ovarian cancer cell line (OVCAR8R) as compared to its cisplatin-sensitive syngeneic counte...

Descripción completa

Detalles Bibliográficos
Autores principales: Carmichael, Melissa M., Alchaar, Israa, Davis, Kathleen A., Krevosky, Merideth Kamradt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879449/
https://www.ncbi.nlm.nih.gov/pubmed/36701406
http://dx.doi.org/10.1371/journal.pone.0281009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879449/
https://www.ncbi.nlm.nih.gov/pubmed/36701406
http://dx.doi.org/10.1371/journal.pone.0281009

Ejemplares similares