Cargando…
The small heat shock protein αB-Crystallin protects versus withaferin A-induced apoptosis and confers a more metastatic phenotype in cisplatin-resistant ovarian cancer cells
Since a majority of ovarian tumors recur in a drug-resistant form leaving patients few treatment options, the goal of this study was to explore phenotypic and molecular characteristics of a cisplatin-resistant ovarian cancer cell line (OVCAR8R) as compared to its cisplatin-sensitive syngeneic counte...
Autores principales: | Carmichael, Melissa M., Alchaar, Israa, Davis, Kathleen A., Krevosky, Merideth Kamradt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879449/ https://www.ncbi.nlm.nih.gov/pubmed/36701406 http://dx.doi.org/10.1371/journal.pone.0281009 |
Ejemplares similares
-
Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance
por: Khan, Saad, et al.
Publicado: (2012) -
Withaferin A Alone and in Combination with Cisplatin Suppresses Growth and Metastasis of Ovarian Cancer by Targeting Putative Cancer Stem Cells
por: Kakar, Sham S., et al.
Publicado: (2014) -
Withaferin A Induces Proteasome-Dependent Degradation of Breast Cancer Susceptibility Gene 1 and Heat Shock Factor 1 Proteins in Breast Cancer Cells
por: Zhang, Xuan, et al.
Publicado: (2012) -
Implications of Withaferin A in neurological disorders
por: Ram, Natasha, et al.
Publicado: (2020) -
Withaferin A attenuates ovarian cancer-induced cardiac cachexia
por: Kelm, Natia Q., et al.
Publicado: (2020)