Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings

Impaired lung function in early life is associated with the subsequent development of chronic respiratory disease. Most genetic associations with lung function have been identified in adults of European descent and therefore may not represent those most relevant to pediatric populations and populati...

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Detalles Bibliográficos
Autores principales: Dapas, Matthew, Thompson, Emma E., Wentworth-Sheilds, William, Clay, Selene, Visness, Cynthia M., Calatroni, Agustin, Sordillo, Joanne E., Gold, Diane R., Wood, Robert A., Makhija, Melanie, Khurana Hershey, Gurjit K., Sherenian, Michael G., Gruchalla, Rebecca S., Gill, Michelle A., Liu, Andrew H., Kim, Haejin, Kattan, Meyer, Bacharier, Leonard B., Rastogi, Deepa, Altman, Matthew C., Busse, William W., Becker, Patrice M., Nicolae, Dan, O’Connor, George T., Gern, James E., Jackson, Daniel J., Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879483/
https://www.ncbi.nlm.nih.gov/pubmed/36638096
http://dx.doi.org/10.1371/journal.pgen.1010594

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