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Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed
BACKGROUND: people living with cognitive impairment commonly take multiple medications including potentially inappropriate medications (PIMs), which puts them at risk of medication related harms. AIMS: to explore willingness to have a medication deprescribed of older people living with cognitive imp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879708/ https://www.ncbi.nlm.nih.gov/pubmed/36702513 http://dx.doi.org/10.1093/ageing/afac335 |
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author | Reeve, Emily Bayliss, Elizabeth A Shetterly, Susan Maiyani, Mahesh Gleason, Kathy S Norton, Jonathan D Sheehan, Orla C Green, Ariel R Maciejewski, Matthew L Drace, Melanie Sawyer, Jennifer Boyd, Cynthia M |
author_facet | Reeve, Emily Bayliss, Elizabeth A Shetterly, Susan Maiyani, Mahesh Gleason, Kathy S Norton, Jonathan D Sheehan, Orla C Green, Ariel R Maciejewski, Matthew L Drace, Melanie Sawyer, Jennifer Boyd, Cynthia M |
author_sort | Reeve, Emily |
collection | PubMed |
description | BACKGROUND: people living with cognitive impairment commonly take multiple medications including potentially inappropriate medications (PIMs), which puts them at risk of medication related harms. AIMS: to explore willingness to have a medication deprescribed of older people living with cognitive impairment (dementia or mild cognitive impairment) and multiple chronic conditions and assess the relationship between willingness, patient characteristics and belief about medications. METHODS: cross-sectional study using results from the revised Patients’ Attitudes Towards Deprescribing questionnaire (rPATDcog) collected as baseline data in the OPTIMIZE study, a pragmatic, cluster-randomised trial educating patients and clinicians about deprescribing. Eligible participants were 65+, diagnosed with dementia or mild cognitive impairment, and prescribed at least five-long-term medications. RESULTS: the questionnaire was mailed to 1,409 intervention patients and 553 (39%) were returned and included in analysis. Participants had a mean age of 80.1 (SD 7.4) and 52.4% were female. About 78.5% (431/549) of participants said that they would be willing to have one of their medications stopped if their doctor said it was possible. Willingness to deprescribe was negatively associated with getting stressed when changes are made and with previously having a bad experience with stopping a medication (P < 0.001 for both). CONCLUSION: most older people living with cognitive impairment are willing to deprescribe. Addressing previous bad experiences with stopping a medication and stress when changes are made to medications may be key points to discuss during deprescribing conversations. |
format | Online Article Text |
id | pubmed-9879708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-98797082023-01-31 Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed Reeve, Emily Bayliss, Elizabeth A Shetterly, Susan Maiyani, Mahesh Gleason, Kathy S Norton, Jonathan D Sheehan, Orla C Green, Ariel R Maciejewski, Matthew L Drace, Melanie Sawyer, Jennifer Boyd, Cynthia M Age Ageing Research Paper BACKGROUND: people living with cognitive impairment commonly take multiple medications including potentially inappropriate medications (PIMs), which puts them at risk of medication related harms. AIMS: to explore willingness to have a medication deprescribed of older people living with cognitive impairment (dementia or mild cognitive impairment) and multiple chronic conditions and assess the relationship between willingness, patient characteristics and belief about medications. METHODS: cross-sectional study using results from the revised Patients’ Attitudes Towards Deprescribing questionnaire (rPATDcog) collected as baseline data in the OPTIMIZE study, a pragmatic, cluster-randomised trial educating patients and clinicians about deprescribing. Eligible participants were 65+, diagnosed with dementia or mild cognitive impairment, and prescribed at least five-long-term medications. RESULTS: the questionnaire was mailed to 1,409 intervention patients and 553 (39%) were returned and included in analysis. Participants had a mean age of 80.1 (SD 7.4) and 52.4% were female. About 78.5% (431/549) of participants said that they would be willing to have one of their medications stopped if their doctor said it was possible. Willingness to deprescribe was negatively associated with getting stressed when changes are made and with previously having a bad experience with stopping a medication (P < 0.001 for both). CONCLUSION: most older people living with cognitive impairment are willing to deprescribe. Addressing previous bad experiences with stopping a medication and stress when changes are made to medications may be key points to discuss during deprescribing conversations. Oxford University Press 2023-01-23 /pmc/articles/PMC9879708/ /pubmed/36702513 http://dx.doi.org/10.1093/ageing/afac335 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Research Paper Reeve, Emily Bayliss, Elizabeth A Shetterly, Susan Maiyani, Mahesh Gleason, Kathy S Norton, Jonathan D Sheehan, Orla C Green, Ariel R Maciejewski, Matthew L Drace, Melanie Sawyer, Jennifer Boyd, Cynthia M Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title | Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title_full | Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title_fullStr | Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title_full_unstemmed | Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title_short | Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
title_sort | willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879708/ https://www.ncbi.nlm.nih.gov/pubmed/36702513 http://dx.doi.org/10.1093/ageing/afac335 |
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