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Temporal order judgment of multisensory stimuli in rat and human

We do not fully understand the resolution at which temporal information is processed by different species. Here we employed a temporal order judgment (TOJ) task in rats and humans to test the temporal precision with which these species can detect the order of presentation of simple stimuli across tw...

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Autores principales: Mafi, Fatemeh, Tang, Matthew F., Afarinesh, Mohammad Reza, Ghasemian, Sadegh, Sheibani, Vahid, Arabzadeh, Ehsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879721/
https://www.ncbi.nlm.nih.gov/pubmed/36710957
http://dx.doi.org/10.3389/fnbeh.2022.1070452
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author Mafi, Fatemeh
Tang, Matthew F.
Afarinesh, Mohammad Reza
Ghasemian, Sadegh
Sheibani, Vahid
Arabzadeh, Ehsan
author_facet Mafi, Fatemeh
Tang, Matthew F.
Afarinesh, Mohammad Reza
Ghasemian, Sadegh
Sheibani, Vahid
Arabzadeh, Ehsan
author_sort Mafi, Fatemeh
collection PubMed
description We do not fully understand the resolution at which temporal information is processed by different species. Here we employed a temporal order judgment (TOJ) task in rats and humans to test the temporal precision with which these species can detect the order of presentation of simple stimuli across two modalities of vision and audition. Both species reported the order of audiovisual stimuli when they were presented from a central location at a range of stimulus onset asynchronies (SOA)s. While both species could reliably distinguish the temporal order of stimuli based on their sensory content (i.e., the modality label), rats outperformed humans at short SOAs (less than 100 ms) whereas humans outperformed rats at long SOAs (greater than 100 ms). Moreover, rats produced faster responses compared to humans. The reaction time data further revealed key differences in decision process across the two species: at longer SOAs, reaction times increased in rats but decreased in humans. Finally, drift-diffusion modeling allowed us to isolate the contribution of various parameters including evidence accumulation rates, lapse and bias to the sensory decision. Consistent with the psychophysical findings, the model revealed higher temporal sensitivity and a higher lapse rate in rats compared to humans. These findings suggest that these species applied different strategies for making perceptual decisions in the context of a multimodal TOJ task.
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spelling pubmed-98797212023-01-27 Temporal order judgment of multisensory stimuli in rat and human Mafi, Fatemeh Tang, Matthew F. Afarinesh, Mohammad Reza Ghasemian, Sadegh Sheibani, Vahid Arabzadeh, Ehsan Front Behav Neurosci Behavioral Neuroscience We do not fully understand the resolution at which temporal information is processed by different species. Here we employed a temporal order judgment (TOJ) task in rats and humans to test the temporal precision with which these species can detect the order of presentation of simple stimuli across two modalities of vision and audition. Both species reported the order of audiovisual stimuli when they were presented from a central location at a range of stimulus onset asynchronies (SOA)s. While both species could reliably distinguish the temporal order of stimuli based on their sensory content (i.e., the modality label), rats outperformed humans at short SOAs (less than 100 ms) whereas humans outperformed rats at long SOAs (greater than 100 ms). Moreover, rats produced faster responses compared to humans. The reaction time data further revealed key differences in decision process across the two species: at longer SOAs, reaction times increased in rats but decreased in humans. Finally, drift-diffusion modeling allowed us to isolate the contribution of various parameters including evidence accumulation rates, lapse and bias to the sensory decision. Consistent with the psychophysical findings, the model revealed higher temporal sensitivity and a higher lapse rate in rats compared to humans. These findings suggest that these species applied different strategies for making perceptual decisions in the context of a multimodal TOJ task. Frontiers Media S.A. 2023-01-12 /pmc/articles/PMC9879721/ /pubmed/36710957 http://dx.doi.org/10.3389/fnbeh.2022.1070452 Text en Copyright © 2023 Mafi, Tang, Afarinesh, Ghasemian, Sheibani and Arabzadeh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Behavioral Neuroscience
Mafi, Fatemeh
Tang, Matthew F.
Afarinesh, Mohammad Reza
Ghasemian, Sadegh
Sheibani, Vahid
Arabzadeh, Ehsan
Temporal order judgment of multisensory stimuli in rat and human
title Temporal order judgment of multisensory stimuli in rat and human
title_full Temporal order judgment of multisensory stimuli in rat and human
title_fullStr Temporal order judgment of multisensory stimuli in rat and human
title_full_unstemmed Temporal order judgment of multisensory stimuli in rat and human
title_short Temporal order judgment of multisensory stimuli in rat and human
title_sort temporal order judgment of multisensory stimuli in rat and human
topic Behavioral Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879721/
https://www.ncbi.nlm.nih.gov/pubmed/36710957
http://dx.doi.org/10.3389/fnbeh.2022.1070452
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