Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship

Over a 4-year period, the antimicrobial stewardship team reviewed all positive (PCR+/Tox+) and indeterminate (PCR+/Tox−) cases with the most responsible physician for classification of patients as infection or colonization. Among 501 indeterminate samples, 213 (43%) were considered to be clinical in...

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Autores principales: Lowe, Christopher F., Shakeraneh, Shayan, Lee, Colin, Sharma, Azra, Leung, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879867/
https://www.ncbi.nlm.nih.gov/pubmed/36712476
http://dx.doi.org/10.1017/ash.2022.350
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author Lowe, Christopher F.
Shakeraneh, Shayan
Lee, Colin
Sharma, Azra
Leung, Victor
author_facet Lowe, Christopher F.
Shakeraneh, Shayan
Lee, Colin
Sharma, Azra
Leung, Victor
author_sort Lowe, Christopher F.
collection PubMed
description Over a 4-year period, the antimicrobial stewardship team reviewed all positive (PCR+/Tox+) and indeterminate (PCR+/Tox−) cases with the most responsible physician for classification of patients as infection or colonization. Among 501 indeterminate samples, 213 (43%) were considered to be clinical infection, suggesting the need for ongoing clinical assessment of indeterminates.
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spelling pubmed-98798672023-01-28 Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship Lowe, Christopher F. Shakeraneh, Shayan Lee, Colin Sharma, Azra Leung, Victor Antimicrob Steward Healthc Epidemiol Concise Communication Over a 4-year period, the antimicrobial stewardship team reviewed all positive (PCR+/Tox+) and indeterminate (PCR+/Tox−) cases with the most responsible physician for classification of patients as infection or colonization. Among 501 indeterminate samples, 213 (43%) were considered to be clinical infection, suggesting the need for ongoing clinical assessment of indeterminates. Cambridge University Press 2022-12-15 /pmc/articles/PMC9879867/ /pubmed/36712476 http://dx.doi.org/10.1017/ash.2022.350 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Concise Communication
Lowe, Christopher F.
Shakeraneh, Shayan
Lee, Colin
Sharma, Azra
Leung, Victor
Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title_full Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title_fullStr Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title_full_unstemmed Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title_short Optimizing the interpretation of Clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
title_sort optimizing the interpretation of clostridioides difficile two-step diagnostic algorithm results through antimicrobial stewardship
topic Concise Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879867/
https://www.ncbi.nlm.nih.gov/pubmed/36712476
http://dx.doi.org/10.1017/ash.2022.350
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