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The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex

Mitophagy removes defective or superfluous mitochondria via selective autophagy. In yeast, the pro-mitophagic protein Atg32 localizes to the mitochondrial surface and interacts with the scaffold protein Atg11 to promote degradation of mitochondria. Although Atg32-Atg11 interactions are thought to be...

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Detalles Bibliográficos
Autores principales: Onishi, Mashun, Kubota, Mitsutaka, Duan, Lan, Tian, Yuan, Okamoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880027/
https://www.ncbi.nlm.nih.gov/pubmed/36697253
http://dx.doi.org/10.26508/lsa.202201640