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The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex
Mitophagy removes defective or superfluous mitochondria via selective autophagy. In yeast, the pro-mitophagic protein Atg32 localizes to the mitochondrial surface and interacts with the scaffold protein Atg11 to promote degradation of mitochondria. Although Atg32-Atg11 interactions are thought to be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880027/ https://www.ncbi.nlm.nih.gov/pubmed/36697253 http://dx.doi.org/10.26508/lsa.202201640 |