Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds

The widespread conversion of synthetic receptors into luminescent sensors has been achieved via the use of fluorescent-indicator displacement assays (F-IDAs). Due to their rigid structures and efficient binding affinities, cucurbit[n]urils, combined with a variety of fluorescent guests, have gained...

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Autores principales: Duan, Qunpeng, Chen, Ran, Deng, Su, Yang, Cheng, Ji, Xinxin, Qi, Gege, Li, Hui, Li, Xiaohan, Chen, Shihao, Lou, Mengen, Lu, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880063/
https://www.ncbi.nlm.nih.gov/pubmed/36711232
http://dx.doi.org/10.3389/fchem.2023.1124705
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author Duan, Qunpeng
Chen, Ran
Deng, Su
Yang, Cheng
Ji, Xinxin
Qi, Gege
Li, Hui
Li, Xiaohan
Chen, Shihao
Lou, Mengen
Lu, Kui
author_facet Duan, Qunpeng
Chen, Ran
Deng, Su
Yang, Cheng
Ji, Xinxin
Qi, Gege
Li, Hui
Li, Xiaohan
Chen, Shihao
Lou, Mengen
Lu, Kui
author_sort Duan, Qunpeng
collection PubMed
description The widespread conversion of synthetic receptors into luminescent sensors has been achieved via the use of fluorescent-indicator displacement assays (F-IDAs). Due to their rigid structures and efficient binding affinities, cucurbit[n]urils, combined with a variety of fluorescent guests, have gained extensive utilization in fluorescent-indicator displacement assays for sensing non-fluorescent or weakly fluorescent organic compounds (analytes) in a selective and specific manner. This mini-review summarizes recent advances in the design of cucurbit[n]uril-based fluorescent-indicator displacement assays and discusses the current challenges and future prospects in this area.
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spelling pubmed-98800632023-01-28 Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds Duan, Qunpeng Chen, Ran Deng, Su Yang, Cheng Ji, Xinxin Qi, Gege Li, Hui Li, Xiaohan Chen, Shihao Lou, Mengen Lu, Kui Front Chem Chemistry The widespread conversion of synthetic receptors into luminescent sensors has been achieved via the use of fluorescent-indicator displacement assays (F-IDAs). Due to their rigid structures and efficient binding affinities, cucurbit[n]urils, combined with a variety of fluorescent guests, have gained extensive utilization in fluorescent-indicator displacement assays for sensing non-fluorescent or weakly fluorescent organic compounds (analytes) in a selective and specific manner. This mini-review summarizes recent advances in the design of cucurbit[n]uril-based fluorescent-indicator displacement assays and discusses the current challenges and future prospects in this area. Frontiers Media S.A. 2023-01-13 /pmc/articles/PMC9880063/ /pubmed/36711232 http://dx.doi.org/10.3389/fchem.2023.1124705 Text en Copyright © 2023 Duan, Chen, Deng, Yang, Ji, Qi, Li, Li, Chen, Lou and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Duan, Qunpeng
Chen, Ran
Deng, Su
Yang, Cheng
Ji, Xinxin
Qi, Gege
Li, Hui
Li, Xiaohan
Chen, Shihao
Lou, Mengen
Lu, Kui
Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title_full Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title_fullStr Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title_full_unstemmed Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title_short Cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
title_sort cucurbit[n]uril-based fluorescent indicator-displacement assays for sensing organic compounds
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880063/
https://www.ncbi.nlm.nih.gov/pubmed/36711232
http://dx.doi.org/10.3389/fchem.2023.1124705
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