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Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca(2+) channels

Voltage-gated Ca(2+) channels (VGCCs) mediate Ca(2+) influx to trigger neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The abundance of VGCCs at AZs regulates neurotransmitter release probability (P(r)), a key presynaptic determinant of synaptic strength. Given t...

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Detalles Bibliográficos
Autores principales:	Cunningham, Karen L., Littleton, J. Troy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880069/ https://www.ncbi.nlm.nih.gov/pubmed/36710932 http://dx.doi.org/10.3389/fnmol.2022.1116729

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