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Development and validation of two bioanalysis methods for the determination of etimicin in human serum and urine by liquid chromatography-tandem mass spectrometry: Applications to a human pharmacokinetic and breakpoint study

Etimicin is a fourth-generation aminoglycoside antibiotic. It has potent activity and low toxicity when employed for the treatment of Gram-negative and Gram-positive bacterial infections. The pharmacokinetics of etimicin in humans have not been elucidated completely. Two liquid chromatography-tandem...

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Detalles Bibliográficos
Autores principales: Cui, Xinge, Zheng, Xin, Ren, Jianwei, Liu, Hongzhong, Jia, Yuan, Wu, Aiguo, Han, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880317/
https://www.ncbi.nlm.nih.gov/pubmed/36713844
http://dx.doi.org/10.3389/fphar.2023.1076046