Cargando…

Increased response to TPF chemotherapy promotes immune escape in hypopharyngeal squamous cell carcinoma

Background: There is an urgent need to identify which patients would benefit from TPF chemotherapy in hypopharyngeal squamous cell carcinoma (HPSCC) and to explore new combinations to improve the treatment effect. Materials and methods: Gene-expression profiles in 15 TPF-sensitive patients were comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ruichen, Yan, Li, Tian, Shu, Zhao, Yang, Zhu, Yi, Wang, Xiaoshen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880322/ https://www.ncbi.nlm.nih.gov/pubmed/36712687 http://dx.doi.org/10.3389/fphar.2022.1097197

Ejemplares similares

Development and Validation of a Prognostic Nomogram for Hypopharyngeal Carcinoma
por: Tian, Shu, et al.
Publicado: (2021)

Combination of TPF regimen and cinobufotalin inhibits proliferation and induces apoptosis in human hypopharyngeal and laryngeal squamous cell carcinoma cells
por: Shen, Xixi, et al.
Publicado: (2018)

Effect of CADM1 on TPF-induced chemotherapy in laryngeal squamous cell carcinoma
por: Nie, Jiani, et al.
Publicado: (2023)

Microarray gene expression analysis of chemosensitivity for docetaxel, cisplatin and 5-fluorouracil (TPF) combined chemotherapeutic regimen in hypopharyngeal squamous cell carcinoma
por: Lian, Meng, et al.
Publicado: (2017)

TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma
por: Leduc, Charlotte, et al.
Publicado: (2018)

Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression
por: Meng, Ying, et al.
Publicado: (2022)

Neoadjuvant modified TPF (docetaxel, cisplatin, fluorouracil) for patients unfit to standard TPF in locally advanced head and neck squamous cell carcinoma: a study of 48 patients
por: Fayette, Jérôme, et al.
Publicado: (2016)

Two postoperative chemotherapies for gastric cancer: FOLFOX4 vs. TPF
por: Xie, Honghu, et al.
Publicado: (2019)

Long-term results of a randomized phase III trial of TPF induction chemotherapy followed by surgery and radiation in locally advanced oral squamous cell carcinoma
por: Zhong, Lai-ping, et al.
Publicado: (2015)

Pparg may Promote Chemosensitivity of Hypopharyngeal Squamous Cell Carcinoma
por: Lian, Meng, et al.
Publicado: (2020)

Pretreatment monocyte counts and neutrophil counts predict the risk for febrile neutropenia in patients undergoing TPF chemotherapy for head and neck squamous cell carcinoma
por: Shimanuki, Marie, et al.
Publicado: (2018)

Variation of PPARG Expression in Chemotherapy-Sensitive Patients of Hypopharyngeal Squamous Cell Carcinoma
por: Lian, Meng, et al.
Publicado: (2021)

Prognostic Nomogram for Postoperative Hypopharyngeal Squamous Cell Carcinoma to Assist Decision Making for Adjuvant Chemotherapy
por: Zhang, Di, et al.
Publicado: (2022)

Comparison of TPF and TP Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma Based on TNM Stage and Pretreatment Systemic Immune-Inflammation Index
por: Xiong, Ying, et al.
Publicado: (2021)

Induction TPF followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locally advanced hypopharyngeal cancer: a preliminary analysis of a randomized phase 2 trial
por: Luo, Xi, et al.
Publicado: (2022)

Predictive factors of toxicity of TPF induction chemotherapy for locally advanced head and neck cancers
por: Bernadach, Maureen, et al.
Publicado: (2021)

Endoscopic Resection of Hypopharyngeal Squamous Cell Carcinoma
por: Bok, Gene Hyun, et al.
Publicado: (2013)

Immune Cell Infiltrates and Neutrophil-to-Lymphocyte Ratio in Relation to Response to Chemotherapy and Prognosis in Laryngeal and Hypopharyngeal Squamous Cell Carcinomas
por: Sánchez-Canteli, Mario, et al.
Publicado: (2021)

Antitumor effects of valdecoxib on hypopharyngeal squamous carcinoma cells
por: Trang, Nguyen Thi Kieu, et al.
Publicado: (2022)

Neoadjuvant chemotherapy with different dose regimens of docetaxel, cisplatin and fluorouracil (TPF) for locoregionally advanced nasopharyngeal carcinoma: a retrospective study
por: Jin, Ting, et al.
Publicado: (2017)

HOXA11-AS1 Promotes PD-L1-Mediated Immune Escape and Metastasis of Hypopharyngeal Carcinoma by Facilitating PTBP1 and FOSL1 Association
por: Zhou, Zheng, et al.
Publicado: (2022)

Low p16 Cytoplasmic Staining Predicts Poor Treatment Outcome in Patients with p16-Negative Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving TPF Induction Chemotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2023)

Comparison of therapeutic efficacy and toxicity of docetaxel, cisplatin, and fluorouracil (TPF)-based induction chemotherapy plus concurrent chemoradiotherapy and chemoradiotherapy alone in locally advanced nasopharyngeal carcinoma
por: Chen, Ruijuan, et al.
Publicado: (2021)

TMEM184B promotes proliferation, migration and invasion, and inhibits apoptosis in hypopharyngeal squamous cell carcinoma
por: Lin, Yun, et al.
Publicado: (2022)

Free posterior tibial flap reconstruction for hypopharyngeal squamous cell carcinoma
por: Chen, Fei, et al.
Publicado: (2014)

Predictors of Thyroid Gland Involvement in Hypopharyngeal Squamous Cell Carcinoma
por: Chang, Jae Won, et al.
Publicado: (2015)

Concomitant Extramedullary Plasmacytoma in the Oropharynx and Hypopharyngeal Squamous Cell Carcinoma
por: Sato, Hiroki, et al.
Publicado: (2018)

Treatment patterns and survival outcomes of advanced hypopharyngeal squamous cell carcinoma
por: Tsai, Yao-Te, et al.
Publicado: (2020)

Serum Levels of Stromal Cell-Derived Factor-1α and Vascular Endothelial Growth Factor Predict Clinical Outcomes in Head and Neck Squamous Cell Carcinoma Patients Receiving TPF Induction Chemotherapy
por: Chen, Yen-Hao, et al.
Publicado: (2022)

Phase II study of induction chemotherapy with TPF followed by radioimmunotherapy with Cetuximab and intensity-modulated radiotherapy (IMRT) in combination with a carbon ion boost for locally advanced tumours of the oro-, hypopharynx and larynx - TPF-C-HIT
por: Jensen, Alexandra D, et al.
Publicado: (2011)

Polypeptide Nanogels With Different Functional Cores Promote Chemotherapy of Lung Carcinoma
por: Niu, Kai, et al.
Publicado: (2019)

LC3B in Malignant Cells Correlates With Immune Infiltrate in Hypopharyngeal Squamous Cell Carcinoma
por: Gao, Sifan, et al.
Publicado: (2020)

The functional verification of EGFR-CAR T-cells targeted to hypopharyngeal squamous cell carcinoma
por: Dong, Yi-Han, et al.
Publicado: (2018)

LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma
por: Zhou, Zheng, et al.
Publicado: (2023)

FMS-Related Tyrosine Kinase 3 Ligand Promotes Radioresistance in Esophageal Squamous Cell Carcinoma
por: Zhu, Zuoquan, et al.
Publicado: (2021)

Dose-dense TPF induction chemotherapy for locally advanced head and neck cancer: a phase II study
por: Hsieh, Ching-Yun, et al.
Publicado: (2020)

Treatment of Sinonasal Undifferentiated Carcinoma with TPF and Concurrent Chemo-Radiation: Case Report and Literature Review
por: Barber, Emily, et al.
Publicado: (2019)

STK33 overexpression in hypopharyngeal squamous cell carcinoma: possible role in tumorigenesis
por: Huang, Lingyan, et al.
Publicado: (2015)

Overexpression of long noncoding RNA PEG10 promotes proliferation, invasion and metastasis of hypopharyngeal squamous cell carcinoma
por: Zhao, Miaoqing, et al.
Publicado: (2017)

Cost-Effectiveness Analysis of Camrelizumab Versus Chemotherapy as Second-Line Treatment of Advanced or Metastatic Esophageal Squamous Cell Carcinoma
por: Cai, Hongfu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ag0a0tmhre80p2kfb7rpdou4r6