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“iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives”

The bleeding phenotype of hereditary coagulation disorders is caused by the low or undetectable activity of the proteins involved in hemostasis, due to a broad spectrum of genetic alterations. Most of the affected coagulation factors are produced in the liver. Therefore, two-dimensional (2D) culture...

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Detalles Bibliográficos
Autores principales: Roman, Giacomo, Stavik, Benedicte, Lauritzen, Knut H., Sandset, Per Morten, Harrison, Sean P., Sullivan, Gareth J., Chollet, Maria Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880334/
https://www.ncbi.nlm.nih.gov/pubmed/36711019
http://dx.doi.org/10.3389/fphys.2023.1094249