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“iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives”
The bleeding phenotype of hereditary coagulation disorders is caused by the low or undetectable activity of the proteins involved in hemostasis, due to a broad spectrum of genetic alterations. Most of the affected coagulation factors are produced in the liver. Therefore, two-dimensional (2D) culture...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880334/ https://www.ncbi.nlm.nih.gov/pubmed/36711019 http://dx.doi.org/10.3389/fphys.2023.1094249 |