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DNA methylation-based patterns for early diagnostic prediction and prognostic evaluation in colorectal cancer patients with high tumor mutation burden

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy has proven to be a promising treatment for colorectal cancer (CRC). We aim to investigate the relationship between DNA methylation and tumor mutation burden (TMB) by integrating genomic and epigenetic profiles to precisely identify clinical benef...

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Detalles Bibliográficos
Autores principales:	Huang, Hao, Cao, Weifan, Long, Zhiping, Kuang, Lei, Li, Xi, Feng, Yifei, Wu, Yuying, Zhao, Yang, Chen, Yinggang, Sun, Peng, Peng, Panxin, Zhang, Jinli, Yuan, Lijun, Li, Tianze, Hu, Huifang, Li, Gairui, Yang, Longkun, Zhang, Xing, Hu, Fulan, Sun, Xizhuo, Hu, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880489/ https://www.ncbi.nlm.nih.gov/pubmed/36713578 http://dx.doi.org/10.3389/fonc.2022.1030335

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