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A novel assay that characterizes properdin function shows neutrophil-derived properdin has a distinct oligomeric distribution

Properdin acts as an essential positive regulator of the alternative pathway of complement by stabilizing enzymatic convertases. Identical properdin monomers form head-to-tail associations of oligomers in a reported 20:54:26 ratio (most often described as an approximate 1:2:1 ratio) of tetramers (P(...

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Detalles Bibliográficos
Autores principales:	Moore, Sara R., Menon, Smrithi S., Galwankar, Neeti S., Khuder, Sadik A., Pangburn, Michael K., Ferreira, Viviana P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880526/ https://www.ncbi.nlm.nih.gov/pubmed/36713423 http://dx.doi.org/10.3389/fimmu.2022.918856

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