Cargando…

3’UTR Diversity: Expanding Repertoire of RNA Alterations in Human mRNAs

Genomic information stored in the DNA is transcribed to the mRNA and translated to proteins. The 3′ untranslated regions (3′UTRs) of the mRNA serve pivotal roles in post-transcriptional gene expression, regulating mRNA stability, translation, and localization. Similar to DNA mutations producing aber...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Dawon, Jeong, Sunjoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2023
Materias:	Minireview
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880603/ https://www.ncbi.nlm.nih.gov/pubmed/36697237 http://dx.doi.org/10.14348/molcells.2023.0003

Ejemplares similares

Regulating highly dynamic unstructured proteins and their coding mRNAs
por: Ma, Buyong, et al.
Publicado: (2009)

Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression
por: Yeh, Hsin-Sung, et al.
Publicado: (2016)

SR Proteins: Binders, Regulators, and Connectors of RNA
por: Jeong, Sunjoo
Publicado: (2017)

DDX3 depletion represses translation of mRNAs with complex 5′ UTRs
por: Calviello, Lorenzo, et al.
Publicado: (2021)

Mutation Hotspots in the β-Catenin Gene: Lessons from the Human Cancer Genome Databases
por: Kim, Sewoon, et al.
Publicado: (2019)

Rous Sarcoma Virus RNA Stability Element Inhibits Deadenylation of mRNAs with Long 3′UTRs
por: Balagopal, Vidya, et al.
Publicado: (2017)

Long 3′-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae
por: Kebaara, Bessie W., et al.
Publicado: (2009)

A catalog of stability-associated sequence elements in 3' UTRs of yeast mRNAs
por: Shalgi, Reut, et al.
Publicado: (2005)

G-quadruplexes formation in the 5’UTRs of mRNAs associated with colorectal cancer pathways
por: Jodoin, Rachel, et al.
Publicado: (2018)

ARED-Plus: an updated and expanded database of AU-rich element-containing mRNAs and pre-mRNAs
por: Bakheet, Tala, et al.
Publicado: (2018)

Long 3'UTR of Nurr1 mRNAs is targeted by miRNAs in mesencephalic dopamine neurons
por: Pereira, Luis Alberto, et al.
Publicado: (2017)

Human immune repertoire in hepatitis B virus infection
por: Zhan, Qiao, et al.
Publicado: (2021)

Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation
por: Essig, Katharina, et al.
Publicado: (2018)

Aire Gene Influences the Length of the 3′ UTR of mRNAs in Medullary Thymic Epithelial Cells
por: Oliveira, Ernna H., et al.
Publicado: (2020)

β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3′-UTR
por: Lee, Hee Kyu, et al.
Publicado: (2006)

Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3′UTRs
por: Mühlemann, Oliver
Publicado: (2016)

RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3′ UTRs
por: Di Giammartino, Dafne Campigli, et al.
Publicado: (2014)

Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3′ UTRs
por: Flora, Pooja, et al.
Publicado: (2018)

eIF3 engages with 3’-UTR termini of highly translated mRNAs in neural progenitor cells
por: Mestre-Fos, Santi, et al.
Publicado: (2023)

Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs
por: Gasparello, Jessica, et al.
Publicado: (2021)

New Links between mRNA Polyadenylation and Diverse Nuclear Pathways
por: Di Giammartino, Dafne Campigli, et al.
Publicado: (2014)

Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
por: Wegrzyn, Jill L, et al.
Publicado: (2008)

A Translation Initiation Element Specific to mRNAs with Very Short 5′UTR that Also Regulates Transcription
por: Elfakess, Rofa, et al.
Publicado: (2008)

Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference
por: Santhanam, Arti N., et al.
Publicado: (2009)

Precise tuning of bacterial translation initiation by non-equilibrium 5′-UTR unfolding observed in single mRNAs
por: Ray, Sujay, et al.
Publicado: (2022)

Brain-expressed 3′UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs
por: Wehrspaun, Claudia C., et al.
Publicado: (2014)

Nuclear UPF1 Is Associated with Chromatin for Transcription-Coupled RNA Surveillance
por: Hong, Dawon, et al.
Publicado: (2019)

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR
por: Culjkovic, Biljana, et al.
Publicado: (2005)

Correction: Role of 3′UTRs in the Translation of mRNAs Regulated by Oncogenic eIF4E—A Computational Inference
por: Santhanam, Arti N., et al.
Publicado: (2009)

3′ UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts
por: Spies, Noah, et al.
Publicado: (2013)

The 3’UTRs of Myelin Basic Protein mRNAs Regulate Transport, Local Translation and Sensitivity to Neuronal Activity in Zebrafish
por: Torvund-Jensen, Julie, et al.
Publicado: (2018)

Expanding the mitochondrial interactome
por: Shutt, Timothy E, et al.
Publicado: (2007)

Scan for Motifs: a webserver for the analysis of post-transcriptional regulatory elements in the 3′ untranslated regions (3′ UTRs) of mRNAs
por: Biswas, Ambarish, et al.
Publicado: (2014)

nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
por: Gandin, Valentina, et al.
Publicado: (2016)

MicroRNA-mediated repression of nonsense mRNAs
por: Zhao, Ya, et al.
Publicado: (2014)

The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from gene loci
por: Singh, Anand K, et al.
Publicado: (2019)

mRNAs held back
por: LeBrasseur, Nicole
Publicado: (2006)

Stress management for mRNAs
por: Short, Ben
Publicado: (2010)

Untranslated regions of mRNAs
por: Mignone, Flavio, et al.
Publicado: (2002)

β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3′-UTR and interacts with HuR in colon cancer cells
por: Kim, Inae, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_111v77tbok712dkctthflfm1q2