Liquid Droplet Aging and Seeded Fibril Formation of the Cytotoxic Granule Associated RNA Binding Protein TIA1 Low Complexity Domain

[Image: see text] Protein domains biased toward a few amino acid types are vital for the formation of biomolecular condensates in living cells. These membraneless compartments are formed by molecules exhibiting a range of molecular motions and structural order. Missense mutations increase condensate...

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Detalles Bibliográficos
Autores principales: Wittmer, Yuuki, Jami, Khaled M., Stowell, Rachelle K., Le, Truc, Hung, Ivan, Murray, Dylan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881004/
https://www.ncbi.nlm.nih.gov/pubmed/36638831
http://dx.doi.org/10.1021/jacs.2c08596

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