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The Potential Role of Hypoxia-Inducible Factor-1 in the Progression and Therapy of Central Nervous System Diseases

Hypoxia-inducible factor-1 (HIF-1) is a heterodimer protein composed of an oxygen-regulated functional subunit, HIF-1α, and a structural subunit, HIF-1β, belonging to the basic helix-loop-helix family. Strict regulation of HIF-1 protein stability and subsequent transcriptional activity involves vari...

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Detalles Bibliográficos
Autores principales: Chen, Hongxiu, Ma, Di, Yue, Feixue, Qi, Yajie, Dou, Manman, Cui, Liuping, Xing, Yingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881070/
https://www.ncbi.nlm.nih.gov/pubmed/34325641
http://dx.doi.org/10.2174/1570159X19666210729123137