An Acute Presentation of Epstein-Barr Virus (EBV) Infection in an Immunocompromised Gentleman

Epstein-Barr virus (EBV) is a relevant cause of many clinical manifestations with a range of malignant and non-malignant presentations. This is particularly important to consider in immunosuppressed individuals. We present a case of a 36-year-old individual with ulcerative colitis who was in remissi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattacharjee, Shaumick, Ali, Abuobeida, Sayed, Saber, Siyal, Tahmina, Das, Tapas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881071/
https://www.ncbi.nlm.nih.gov/pubmed/36721558
http://dx.doi.org/10.7759/cureus.33036
Descripción
Sumario:Epstein-Barr virus (EBV) is a relevant cause of many clinical manifestations with a range of malignant and non-malignant presentations. This is particularly important to consider in immunosuppressed individuals. We present a case of a 36-year-old individual with ulcerative colitis who was in remission whilst taking mercaptopurine. The patient presented with weight loss, night sweats, and significant laboratory serum abnormalities on monitoring. Relevant investigations into his presentation ruled out a malignant feature, but his serology confirmed infection with EBV with the spread of infection to the liver and bone marrow. Overall, we identify a notable yet relevant clinical expression of EBV infection in the context of an immunosuppressed individual.

Ejemplares similares