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Transient Opening of the Blood-Brain Barrier by Vasoactive Peptides to Increase CNS Drug Delivery: Reality Versus Wishful Thinking?

Background: The blood-brain barrier inhibits the central nervous system penetration of 98% of small molecule drugs and virtually all biologic agents, which has limited progress in treating neurologic disease. Vasoactive peptides have been shown in animal studies to transiently disrupt the blood-brai...

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Detalles Bibliográficos
Autores principales: Smith-Cohn, Matthew A., Burley, Nicholas B., Grossman, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881081/
https://www.ncbi.nlm.nih.gov/pubmed/35100958
http://dx.doi.org/10.2174/1570159X20999220131163504