Cargando…

7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development

7,8-Dihydroxyflavone (7,8-DHF) is a kind of natural flavonoid with the potential to cross the blood-brain barrier. 7,8-DHF effectively mimics the effect of brain-derived neurotrophic factor (BDNF) in the brain to selectively activate tyrosine kinase receptor B (TrkB) and downstream signaling pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Shaojie, Zhu, Guoqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881092/ https://www.ncbi.nlm.nih.gov/pubmed/34525922 http://dx.doi.org/10.2174/1570159X19666210915122820

Ejemplares similares

7,8-Dihydroxyflavone Enhances Cue-Conditioned Alcohol Reinstatement in Rats
por: Hogarth, Samuel J., et al.
Publicado: (2020)

Synapse‐selective rapid potentiation of hippocampal synaptic transmission by 7,8‐dihydroxyflavone
por: Kobayashi, Katsunori, et al.
Publicado: (2018)

Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase
por: Liu, Yun-Chin, et al.
Publicado: (2020)

The TrkB agonist, 7,8-dihydroxyflavone, impairs fracture healing in mice
por: Johnstone, Maddison R., et al.
Publicado: (2021)

Effect of 7,8-Dihydroxyflavone as an Antioxidant on In Vitro Maturation of Oocytes and Development of Parthenogenetic Embryos in Pigs
por: CHOI, Ji-Yei, et al.
Publicado: (2013)

Low-dose 7,8-Dihydroxyflavone Administration After Status Epilepticus Prevents Epilepsy Development
por: Guarino, Annunziata, et al.
Publicado: (2022)

7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
por: Xue, Fan, et al.
Publicado: (2021)

Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome
por: Sharma, Priyanka, et al.
Publicado: (2022)

Rescue of Long-Term Spatial Memory by 7,8-Dihydroxyflavone in Mice with Reduced Oligodendrogenesis
por: Rawlings-Mortimer, Florence, et al.
Publicado: (2023)

7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents
por: Nie, Shuke, et al.
Publicado: (2019)

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress
por: Cho, Suk Ju, et al.
Publicado: (2019)

Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins
por: Chitranshi, Nitin, et al.
Publicado: (2015)

7,8-Dihydroxyflavone activates Nrf2/HO-1 signaling pathways and protects against osteoarthritis
por: Cai, Dawei, et al.
Publicado: (2019)

Sex-Dependent Effects of 7,8-Dihydroxyflavone on Metabolic Health Are Associated with Alterations in the Host Gut Microbiome
por: Sharma, Priyanka, et al.
Publicado: (2021)

7,8-dihydroxyflavone enhances long-term spatial memory and alters brain volume in wildtype mice
por: Rawlings-Mortimer, Florence, et al.
Publicado: (2023)

3D printed elastic hydrogel conduits with 7,8-dihydroxyflavone release for peripheral nerve repair
por: Wu, Wenbi, et al.
Publicado: (2023)

7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice
por: Tan, Yang, et al.
Publicado: (2016)

7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders
por: Liu, Chaoyang, et al.
Publicado: (2016)

7,8-Dihydroxyflavone improves neuropathological changes in the brain of Tg26 mice, a model for HIV-associated neurocognitive disorder
por: Bryant, Joseph, et al.
Publicado: (2021)

Design and Molecular dynamic Investigations of 7,8-Dihydroxyflavone Derivatives as Potential Neuroprotective Agents Against Alpha-synuclein
por: Thangavel, Mohankumar, et al.
Publicado: (2020)

7,8-Dihydroxyflavone Attenuates Inflammatory Response and Insulin Resistance Induced by the Paracrine Interaction between Adipocytes and Macrophages
por: Shin, Ye-Eun, et al.
Publicado: (2023)

Impact of dietary plant flavonoids on 7,8‐dihydroxyflavone transepithelial transport in human intestinal Caco‐2 cells
por: Chen, Yufeng, et al.
Publicado: (2023)

7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson’s disease
por: Zuo, Li, et al.
Publicado: (2021)

Establishment and Characterization of Stable Zein/Glycosylated Lactoferrin Nanoparticles to Enhance the Storage Stability and in vitro Bioaccessibility of 7,8-Dihydroxyflavone
por: Chen, Yufeng, et al.
Publicado: (2022)

7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells
por: Ju, Won Seok, et al.
Publicado: (2023)

Author Correction: 7,8-Dihydroxyflavone improves neuropathological changes in the brain of Tg26 mice, a model for HIV-associated neurocognitive disorder
por: Bryant, Joseph, et al.
Publicado: (2021)

7,8-Dihydroxyflavone Attenuates Alcohol-Related Behavior in Rat Models of Alcohol Consumption via TrkB in the Ventral Tegmental Area
por: Li, Xin-Xin, et al.
Publicado: (2020)

Author Correction: Design and Molecular dynamic Investigations of 7,8-Dihydroxyflavone Derivatives as Potential Neuroprotective Agents Against Alpha-synuclein
por: Mohankumar, Thangavel, et al.
Publicado: (2020)

Effects of 7,8-Dihydroxyflavone on Lipid Isoprenoid and Rho Protein Levels in Brains of Aged C57BL/6 Mice
por: Ötzkan, Sarah, et al.
Publicado: (2020)

7,8-Dihydroxyflavone protects neurons against oxygen-glucose deprivation induced apoptosis and activates the TrkB/Akt pathway
por: Zhou, Qinxiang, et al.
Publicado: (2022)

Correction: 7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells
por: Ju, Won Seok, et al.
Publicado: (2023)

Increased Levels of C1q in the Prefrontal Cortex of Adult Offspring after Maternal Immune Activation: Prevention by 7,8-Dihydroxyflavone
por: Han, Mei, et al.
Publicado: (2017)

Intake of 7,8-Dihydroxyflavone During Juvenile and Adolescent Stages Prevents Onset of Psychosis in Adult Offspring After Maternal Immune Activation
por: Han, Mei, et al.
Publicado: (2016)

7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1
por: Kim, Ki Cheon, et al.
Publicado: (2013)

Models and methods: a perspective of the impact of six IMI translational data-centric initiatives for Alzheimer’s disease and other neuropsychiatric disorders
por: North, Hilary, et al.
Publicado: (2023)

Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone
por: Valenti, Daniela, et al.
Publicado: (2021)

Editorial: Deep brain stimulation for neuropsychiatric disorders: Current status and perspectives
por: Alho, Eduardo Joaquim Lopes, et al.
Publicado: (2022)

Development, Characterization, Stability and Bioaccessibility Improvement of 7,8-Dihydroxyflavone Loaded Zein/Sophorolipid/Polysaccharide Ternary Nanoparticles: Comparison of Sodium Alginate and Sodium Carboxymethyl Cellulose
por: Chen, Yufeng, et al.
Publicado: (2021)

Crosstalk between the muscular estrogen receptor α and BDNF/TrkB signaling alleviates metabolic syndrome via 7,8-dihydroxyflavone in female mice
por: Zhao, Zhenlei, et al.
Publicado: (2020)

Neuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP(+)-treated Monkeys
por: He, Jingjing, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_59mmif1v50p09atfi6eq07hrmq