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Metabolically-targeted dCas9 expression in bacteria

The ability to restrict gene expression to a relevant bacterial species in a complex microbiome is an unsolved problem. In the context of the human microbiome, one desirable target metabolic activity are glucuronide-utilization enzymes (GUS) that are implicated in the toxic re-activation of glucuron...

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Detalles Bibliográficos
Autores principales:	Pellegrino, Gregory M, Browne, Tyler S, Sharath, Keerthana, Bari, Khaleda A, Vancuren, Sarah J, Allen-Vercoe, Emma, Gloor, Gregory B, Edgell, David R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881133/ https://www.ncbi.nlm.nih.gov/pubmed/36629257 http://dx.doi.org/10.1093/nar/gkac1248

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