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Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair

The DNA damage response (DDR) is essential to maintain genome stability, and its deregulation predisposes to carcinogenesis while encompassing attractive targets for cancer therapy. Chromatin governs the DDR via the concerted interplay among different layers, including DNA, histone post-translationa...

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Detalles Bibliográficos
Autores principales:	Sigismondo, Gianluca, Arseni, Lavinia, Palacio-Escat, Nicolàs, Hofmann, Thomas G, Seiffert, Martina, Krijgsveld, Jeroen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881138/ https://www.ncbi.nlm.nih.gov/pubmed/36629267 http://dx.doi.org/10.1093/nar/gkac1264

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