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Freddie: annotation-independent detection and discovery of transcriptomic alternative splicing isoforms using long-read sequencing

Alternative splicing (AS) is an important mechanism in the development of many cancers, as novel or aberrant AS patterns play an important role as an independent onco-driver. In addition, cancer-specific AS is potentially an effective target of personalized cancer therapeutics. However, detecting AS...

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Detalles Bibliográficos
Autores principales: Orabi, Baraa, Xie, Ning, McConeghy, Brian, Dong, Xuesen, Chauve, Cedric, Hach, Faraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881145/
https://www.ncbi.nlm.nih.gov/pubmed/36478271
http://dx.doi.org/10.1093/nar/gkac1112