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Freddie: annotation-independent detection and discovery of transcriptomic alternative splicing isoforms using long-read sequencing
Alternative splicing (AS) is an important mechanism in the development of many cancers, as novel or aberrant AS patterns play an important role as an independent onco-driver. In addition, cancer-specific AS is potentially an effective target of personalized cancer therapeutics. However, detecting AS...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881145/ https://www.ncbi.nlm.nih.gov/pubmed/36478271 http://dx.doi.org/10.1093/nar/gkac1112 |