How does apolipoprotein E genotype influence the relationship between physical activity and Alzheimer’s disease risk? A novel integrative model

BACKGROUND: Wide evidence suggests that physical activity (PA) confers protection against Alzheimer’s disease (AD). On the other hand, the apolipoprotein E gene (APOE) ε4 allele represents the greatest genetic risk factor for developing AD. Extensive research has been conducted to determine whether...

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Detalles Bibliográficos
Autores principales: de Frutos Lucas, Jaisalmer, Sewell, Kelsey R., García-Colomo, Alejandra, Markovic, Shaun, Erickson, Kirk I., Brown, Belinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881295/
https://www.ncbi.nlm.nih.gov/pubmed/36707869
http://dx.doi.org/10.1186/s13195-023-01170-4

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