Tumor necroptosis-mediated shedding of cell surface proteins promotes metastasis of breast cancer by suppressing anti-tumor immunity

Necroptosis is a form of regulated necrosis and is executed by MLKL when MLKL is engaged in triggering the rupture of cell plasma membrane. MLKL activation also leads to the protease, ADAMs-mediated ectodomain shedding of cell surface proteins of necroptotic cells. Tumor necroptosis often happens in...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoshan, Choksi, Swati, Kwon, Hyung-Joon, Jiao, Delong, Liu, Chengyu, Liu, Zheng-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881343/
https://www.ncbi.nlm.nih.gov/pubmed/36703228
http://dx.doi.org/10.1186/s13058-023-01604-9

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